Several indices of steroid homeostasis and reactivity of the adrenal cortex in patients with cancer of the uterine cervix before and after radiotherapy
Samundzhan, E.M.; Kunitsa, M.T.; Butsan, G.N.
Fiziolohichnyi Zhurnal 22(6): 816-818
1976
ISSN/ISBN: 0015-3311 PMID: 1017501 Document Number: 99008
The indexes of adrenal cortex and steroid homeostasis reactivity were studied in 39 patients with uterine body cancer before and after radiotherapy. The functional activity of the adrenal cortex was judged by diurnal urinary excretion of 17-keto steroids, 11-oxy-17-ketosteroids, dehydroepiandrosterone, androsterone and etiocholanolone. Functional testing with ACTH was done before treatment. The data provided evidence for inhibition of the adrenal cortex toward the end of radiation therapy.