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Study of the action of x-ray contrast substances on the respiratory chain of rat liver mitochondria

Sergeev, P.V.; Obratsov, N.V.; Timofeev, A.B.; Khalilov, E.M.

Farmakologiia i Toksikologiia 40(5): 591-595

1977

ISSN/ISBN: 0014-8318
PMID: 923782
Document Number: 123742
Subject to study was the influence of roentgen-contrast media on the respiration and linked with it phosphorylation in the mitochondria of the rats' liver. Triotrast, cardiotrast, bilignost and endografin are shown to produce no effect on the oxidative phosphorylation in concentrations that can be built up following their administration "in vivo", but inhibit the respiratory mitochondrial chain. Triombrin, urotrast and iodamide have no effect on the mitochondria.

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