Effect of x-ray contrast substances on the metabolism of xenobiotics and steroid hormones by rat liver microsomes
Sergeev, P.V.; Bol'shev, V.N.
Farmakologiia i Toksikologiia 41(3): 331-333
1978
ISSN/ISBN: 0014-8318 PMID: 658383 Document Number: 125192
Uro- and cholecystographic contrast media are shown to be capable of changing the rate of oxidative hydroxylation of amidopyrine and steroid hormones. The degree and duration of the diminishing rate of the xenobiotics and steroids metabolism are determined by concentrations of the X-ray contrast media in hepatic cells and the rate of their clearance.