Behavior of adenine nucleotides in stored blood with addition of adenine and guanosine
Stigge, V.; Seidel, B.
Acta Biologica et Medica Germanica 36(3-4): 549-553
1977
ISSN/ISBN: 0001-5318 PMID: 596063 Document Number: 123514
ACD stored blood was substituted with adenine, guanosine or both during usual storage conditions. In weekly intervals concentrations of ATP, ADP and AMP were estimated. From the obtained values it was suggested that the substitutions of adenine and guanosine probably lead to synthesis of the three measured adenine nucleotides. The apparent additive effect of adenine and guanosine upon ATP concentration probably is caused by the simultaneous measurement of GTP and ATP in the used nonspecific method. Under these conditions GTP would have significance for the survival of erythrocytes stored in ACD-AG-medium.