Microscopical and electron microscopical studies of lymphocyte-tumour-cell interaction in monolayer cultures of malignant human tumours
Schönfelder, M.; Wildführ, W.
Zentralblatt für Allgemeine Pathologie U. Pathologische Anatomie 121(4-5): 368-380
1977
ISSN/ISBN: 0044-4030 PMID: 919821 Document Number: 123248
The interaction of lymphoid cells with isogenic malignant human tumours--cultivated as monolayer--was studies by light and electron microscopy. It was shown that an intimate contact was established between lymphoid cells and tumour cells leading to partial confluence of cytoplasmatic structures. This process is the condition of both tumour cell destruction, and also of lymphoid cells. Quantitative problems of immunological tumour cell destruction are discussed.