Ultrastructural analysis of the effect of alloxan on the insular apparatus of the pancreas in amphibia
Iaglov, V.V.
Problemy Endokrinologii 23(3): 87-89
1977
ISSN/ISBN: 0375-9660 PMID: 329271 Document Number: 123239
Administration of alloxan to Rana temporaria in a dose of 300 mg/kg caused a complex of changes in the pancreas. Degranulation of .beta.-cells, of acino-islar cells of .beta. type, and of exocrine pancreocytes; edema of the secretory granules, lysosome activation, and disturbance of the secretory cycle course reactions which were irreversible in the majority of cells were observed.
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