Lipid composition of cutaneous lesions in different types of xanthomatosis
Ferrando, J.; Corominas Vilardell, A.
Medicina Cutanea Ibero-Latino-Americana 5(6): 415-424
1977
ISSN/ISBN: 0210-5187 PMID: 368463 Document Number: 122457
Twenty one specimens of cutaneous xanthomas from different types of hyperlipoproteinaemic and normolipidemic xanthomatosis were obtained and analyzed by thin layer chromatography. After separation and development, the areas were determinated by densitometry, and the results are given in percentages for each development. Acording to the results, the following data are of interest: -- Recents xanthomas have greater amount of lipids. -- Cholesterol esters (EC) are prevalent in xanthomas and in normal skin the triglycerides fraction. -- Monoenoic esters (EM) are prevalent on EC chromatography, like in normal skin. -- Finally, there are not significant variations between lipid composition of xanthomas in the different Xanthomatosis.