Kinetics of drug decomposition. Part 46. Photooxidation and photolysis of some perazine derivatives
Pawelczyk, E.; Marciniec, B.
Polish Journal of Pharmacology and Pharmacy 29(2): 137-142
1977
ISSN/ISBN: 0301-0244 PMID: 16254 Document Number: 122295
The rate and type of the photochemical degradation of perazine derivatives in acidic aqueous solutions depends upon the nature of the substituent at C2 atom. Free perazine degrades by two parallel reactions, namely a fast reversible first-order photooxidation and a slow zero-order photolysis. An introduction of the substituent in the C2 position results frequently in the elimination of one of these reactions.