Gonadotropin secretion and hypothyroidism
Buchanan, G.C.; Tredway, D.R.; Pittard, J.C.; Daane, T.A.
Obstetrics and Gynecology 50(4): 392-396
1977
ISSN/ISBN: 0029-7844 PMID: 904799 Document Number: 120960
Hypothyroidism is generally associated with hypogonadotropism. Occasionally, however, increased gonadotropin concentrations are encountered. The mechanisms, presumably hypothalamic, which determine the gonadotropin shift are unclear. A case report of hyperprolactinemic hypothyroidism with associated hypergonadotropism is presented. The previous literature is reviewed. It appears that hypothyroidism is generally associated with a decrease in the gonadogropin secretion. However, hypothyroidism with exxagerated hTSH secretin and hyperprolactinemia can be associated with increased gonadotropin secretion.