The effect of melatonin and corpus pineale extract on serum electrolytes in the rat
Csaba, G.; Bókay, J.
Acta Biologica Academiae Scientiarum Hungaricae 28(1): 143-144
1977
ISSN/ISBN: 0001-5288 PMID: 602569 Document Number: 120286
Both melatonin and pineal extract act in the same way, viz., by decreasing the levels of Ca2+ and Mg2+ and increasing the phosphate values. The effect develops slowly, a significant difference appears after 3 h in the case of melatonin, and after 60 min in the case of the pineal extract. Taking into account the similar tendency, it seems likely that melatonin is the active substance in the extract, too. The quantitative difference may be ascribed to a higher melatonin content of the pineal extract. In the case of the Mg2+ values the pineal showed values at the border of significance after 60 min and 3 h however, it did not deviate quantitatively from the melatonin effect, only the spreading was higher.