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Radiopaque contrast media. XLIV - Preclinical studies with a new nonionic contrast agent

Felder, E.; Pitrè, D.; Tirone, P.

Il Farmaco; Edizione Scientifica 32(11): 835-844

1977

ISSN/ISBN: 0430-0920
PMID: 923795
Document Number: 118763
L-5-alpha-hydroxypropionylamino-2,4,6-triiodoisophthalic acid di-(1,3-dihydroxy-2-propylamide), abbreviated Iopamidol, a new non-ionic water soluble contrast agent for angiography, myelography, ventriculography and for contrast reinforced computer-assisted axial tomography is described. Extensive preclinical testing showed favorable physico-chemical features of the new compound, low systemic toxicity, excellent cardiovascular and renal tolerability, very mild effects on the blood-brain barrier and on nervous tissue.

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