Ultrastructural changes in plague microbes, strain EV, and splenic cells of guinea pigs in their interaction in vitro
Isupov, I.V.; Kenig, E.E.; Zhukov, V.G.; Konstantinova, N.S.; Zemtsova, I.N.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 5: 55-58
1977
ISSN/ISBN: 0372-9311 PMID: 331769 Document Number: 114030
Dilatation of the endoplasmic reticulum cavities, an increase in the number of ribosomes near bacteria, deformation of mitochondria and coarsening of cristae were revealed in phagocytosis of Past. pestis, strain EV, by reticular cells in the tissue culture of the spleen of intact guinea pigs. Lipophanerous "reticular" inclusions were found in the differentiated reticular cells of the infected cultures. In the reticular cell cytoplasma besides the intact bacteria there were revealed Past. pestis at the initial stages of involution.