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Constitution of scheffleroside: a spermicidal saponin from Schefflera capitata

Jain, G.K.; Sarin, J.P.; Khanna, N.M.

Indian Journal of Chemistry. Sect. B 15(12): 1139-1141

1977

ISSN/ISBN: 0376-4699
PMID: 12260877
Document Number: 112923
While screening Indian plants for biological activities, it was observed that a 2% aqueous solution of the crude 70% aqueous ethanolic extract of Schefflera capitata showed significant activity against both rat and human spermatozoa. The new saponin, melting point 230-232 degrees, gives on acid hydrolysis D(+)-fucose (1 mole), D(+)-galactose (1 mole), D(+)-glucoronic acid (1 mole) and echinocystic acid (1 mole). Its structure has been tentatively assigned to scheffleroside.

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