In vitro effect of transfer factor on active rosettes and leucocyte migration of patients with cancer

Nékám, K.; Kalmár, L.; Gergely, P.; Kelemen, G.; Fekete, B.; Láng, I.; Lévai, J.; Petrányi, G.Y.

Clinical and Experimental Immunology 27(3): 416-420

1977


ISSN/ISBN: 0009-9104
PMID: 324669
Document Number: 112577
The in vitro effect of transfer factor (TF) and its fractions obtained by gel filtration was studied on the active rosettes and leukocyte migration inhibition. TF and 1 fraction (IV) restored the reactivity of lymphocytes from tumor-bearing patients to tuberculin and Candida antigens in the leukocyte migration assay. TF and fraction IV enhanced the number of active rosettes of tumor-bearing patients; no such effect was observed on lymphocytes of patients with active SLE or controls.

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