Effect of somatostatin on canine exocrine pancreas secretion stimulated by pancreozymin, secretin or test meal
Kayasseh, L.; Stalder, G.A.; Gyr, K.; Rittmann, W.W.; Girard, J.
Schweizerische Medizinische Wochenschrift 107(15): 541-542
1977
ISSN/ISBN: 0036-7672 PMID: 857313 Document Number: 112276
In 4 dogs with pancreatic and gastric fistulae the effect of somatostatin (SST) on the pancreas was investigated during stimulation by pancreozymin-secretin or by a test meal. The pancreozymin-secretin-induced enzyme output and bile flow, as well as the enzyme concentration and duodenal volume during test meal stimulation were significantly reduced by SST. SST caused a less marked decrease in bicarbonate concentration, while volume and bicarbonate output did not change.