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Activity of key enzymes of glycolysis in the rat liver during the development of experimental myocardial necrosis

Lukoshiavichius, L.I.; Grigaliunene, V.I.; Prashkiavichius, A.K.

Kardiologiia 17(8): 133-136

1977

ISSN/ISBN: 0022-9040
PMID: 144817
Document Number: 111710
Hexokinase, glucokinase, and phosphofructokinase activity in supernatant hepatic fluid obtained by centrifugation of the homogenate at 20,000 g for 20 minutes was studied during the development of experimental necrosis of the heart muscle. The activity of these enzymes was lowest in the 12th and 24th hour following arterial occlusion. Phosphofructokinase and glucokinase activity returned to the initial level on the 6th and 9th days, respectively; hexokinase activity was still diminished after the 12th day.

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