Pharmacokinetics of antidepressants: why and how they are relevant to treatment
Preskorn, S.H.
Journal of Clinical Psychiatry 54(Suppl): 14-34; Discussion 55-56
1993
ISSN/ISBN: 0160-6689 PMID: 8407856 Document Number: 1117
The pharmacokinetics of antidepressants are reviewed with special emphasis on clinical applicability. There are substantial pharmacokinetic differences among the five major classes. Pharmacokinetic differences between members of a specific class are usually modest except for serotonin selective reuptake inhibitors. Between members of this class pharmacokinetic differences are the major distinguishing variables and have clinically important consequences.
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