Adverse Effects of Antidepressants and their Treatment
Kuriyama, T.; Kawamata, T.
Masui. Japanese Journal of Anesthesiology 65(7): 718-723
2016
ISSN/ISBN: 0021-4892 PMID: 30358303 Document Number: 686685
Antidepressants are used for treatment of not only major depression but also for treatment of neuropathic pain. In guidelines for pharmacological treatment of neuropathic pain, tricyclic antidepressants and sero- tonin noradrenaline reuptake inhibitors are listed as the first line choice and second line choice, respectively. However, antidepressants act on several kinds of neu- ronal receptors, resulting in various adverse effects. In this article, we review common adverse effects of anti- depressant drugs and the prevention and treatments of these adverse effects.