Results of treatment of dysentery patients with streptomycin-dependent vaccine in comparison with other methods of treatment
Iushchuk, N.D.; Kichik, E.I.; Sergeev, V.V.; Godovannyĭ, B.A.; Tumanov, F.A.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 11: 90-94
1977
ISSN/ISBN: 0372-9311 PMID: 339618 Document Number: 111527
Comparative study of various methods of treatment was carried out on 777 patients suffering from acute dysentery with a bacteriologically confirmed diagnosis. To assess the therapeutic efficacy, along with consideration of clinical signs of the disease, immunoglobulin level was examined in the blood and coprofiltrates; also the state of reparative processes in the mucosa was appreciated by the histological examination of the biopsy material. Results of the work carried out indicated the inexpediency of the treatment of this disease with a combination of levomycetin and phthalazol. The use of live streptomycin-dependent dysentery vaccine was indicated in protracted torpid dysentery and was of no avail in acute form of the disease. A good therapeutic effect was observed with the application of pathogenetic therapy alone.