Autologous chondrocytes implantation with three-dimensional collagen scaffold
Kasemkijwattana, C.; Kesprayura, S.; Chaipinyo, K.; Chanlalit, C.; Chansiri, K.
Journal of the Medical Association of Thailand 92(10): 1282-1286
2009
ISSN/ISBN: 0125-2208 PMID: 19845234 Document Number: 11116
The authors report a patient with large traumatic knee cartilage defects treated with autologous chondrocytes implantation (ACI) in three-dimensional collagen scaffold. A patient with grade 3-4 according to ICRS (International Cartilage Repair Society) Classification System was performed ACI with three-dimensional collagen scaffold. The two-stage procedure was performed First, the cartilage was arthroscopic harvested. The chondrocytes were isolated in the laboratory. Second, the chondrocytes were re-implanted into the defects using three-dimensional collagen scaffold. The patients were clinically evaluated pre-operatively and post operatively and magnetic resonance imaging. The duration of follow-up was 12 months. There was no post operative complication. The clinical evaluations were excellent. The MRI showed the hyaline-like cartilage tissue formation at the defects. The autologous chondrocytes implantation with three-dimensional collagen scaffold showed the excellent outcome. Long-term follow-up is required.
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