Hexobarbital-oxidation in vivo and in vitro in rats with bile duct ligation or ANIT-cholestasis
Brachtel, D.; Gallenkamp, H.; Richter, E.
Zeitschrift für Gastroenterologie 15(6): 378-380
1977
ISSN/ISBN: 0044-2771 PMID: 888487 Document Number: 110849
Pharmacokinetics of hexobarbital in rats is not influenced by ligature of the common bile duct or by ANIT-cholestasis. Additional in vitro experiments with isolated liver microsomes show only slight changes of hexobarbital metabolism.
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