An investigation into the deposition of inhalation aerosol particles as a function of air flow rate in a modified &apos;Kirk Lung&apos;

Davies, P.J.; Hanlon, G.W.; Molyneux, A.J.; Davies, P.J; Hanlon, G.W; Molyneux, A.J

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An investigation into the deposition of inhalation aerosol particles as a function of air flow rate in a modified 'Kirk Lung'

Davies, P.J.; Hanlon, G.W.; Molyneux, A.J.

Journal of Pharmacy and Pharmacology 28(12): 908-911

1976

ISSN/ISBN: 0022-3573

PMID: 12267

Document Number: 110031

The effect of air flow rate on deposition of inhalation aerosol particles in a modified Kirk Lung studied with 2 commercial products, [Medihaler-iso and Ventolin]. The amount deposited in the mouthpiece and throat regions decreases with increasing flow rate. The amount in the collector rises to maximum of approximately 50%. This material represents the portion therapeutically available to patients with respiratory disorders. Such an apparatus would be useful for routine quality control of the size distribution ratios for inhalation aerosol particles.