Cerebral circulation (measured by isotopes) and acid-base equilibrium of the cerebrospinal fluid during migraine
Saurugg, D.; Schnaberth, G.
Minerva Medica 67(31): 2017-2019
1976
ISSN/ISBN: 0026-4806 PMID: 934548 Document Number: 109306
In migraine patients a considerable metabolic disturbance characterised by a decrease in bicarbonate and an increase in lactate was demonstrated during the migrainous state. Measurements of the cerebral circulation were taken by means of radioactive isotope and showed a distinct decrease in blood supply to the entire brain during the migraine attack. Following forced hyperventilation during the attack-free interval a pathological reactivity with decreased blood flow was found in the hemisphere which had been indicated as the usual site of the migrainous pain.