Fractionation of a preparation of fibrinolytic enzymes "tricholysin" formed from Trichotecium roseum Lk. ex Fr. on carboxymethyl-sephadex C-50
Stepanova, T.N.; Maksimova, R.A.; Iulikova, E.P.; Silaev, A.B.; Andreenko, G.V.
Prikladnaia Biokhimiia i Mikrobiologiia 12(3): 407-410
1976
ISSN/ISBN: 0555-1099 PMID: 136654 Document Number: 108409
A preparation of fibrinolytic enzymes that produced a specific effect on blood fibrinolysis in animals was isolated from the culture liquid filtrate of the fungus Trichothecium roseum. By gel filtration on KM-Sephadex G-50 six fractions differing in their fibrinolytic, esterase and caseinolytic activities were obtained. The most effective fibrinolytic agents were the first and fourth fractions that had high fibrinolytic and esterase activities and a low caseinolytic activity.