About the role of chronic viral infection in etiology of proliferative diseases of the ENT organs
Katinas, E.B.; Riabova, M.A.; Kucherova, L.R.
Vestnik Otorinolaringologii 4: 15-17
2011
ISSN/ISBN: 0042-4668 PMID: 21983660 Document Number: 10688
The role of certain viruses (human papilloma virus, Epstein-Barr virus, cytomegalovirus, and herpes virus) in the development and malignization of some pre-cancer conditions in human ENT organs is considered. The results of genetic (with the use of PCR) and histological studies of tissue biopsies and surgical specimens are presented. A total of 107 patients presenting with prolifertaive diseases of ENT organ mucosa were available for tissue sampling along with 30 other patients with histologically verified cancer of the larynx, pharynx, nasal cavity, and paranasal sinuses. The clinical data obtained are discussed.
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