The influence of low-molecular extracts from heterologous thymus, epiphysis and hypothalamus on the immune response in mice
Belokrylov, G.A.; Morozov, V.G.; Khavinson, V.K.; sofronov, B.N.
Biulleten' Eksperimental'noi Biologii i Meditsiny 81(2): 202-204
1976
ISSN/ISBN: 0365-9615 PMID: 945090 Document Number: 106278
Extracts from bovine tissue were prepared by the acetic acid treatement and purified by gel filtration. All the preparations were injected into CBA mice for 10 days. Extracts from the thymus and the epiphysis proved to increase the number of antibody-forming cells generated in the spleen and the level of serum hemagglutinins in response to the immunization with sheep red cells. As to the hypothalamic extract, it depressed the immune response.