Spironolactone-associated aggravation of renal functional impairment
Neale, T.J.; Lynn, K.L.; Bailey, R.R.
New Zealand Medical Journal 83(559): 147-149
1976
ISSN/ISBN: 0028-8446 PMID: 1064790 Document Number: 105426
Five patients in whom deterioration in renal function was associated with the use of the aldosterone antagonist, spironolactone, are reported. Care in the use of this drug is urged, especially in the elderly. Patients with known renal functional impairment should not receive this agent.
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