A lupus-like reaction to subcutaneous interferon-α at injection sites
Chodkiewicz, H.M.; Cohen, P.R.; Kim, K.B.; Ivan, D.; Gershenwald, J.E.
Journal of Drugs in Dermatology Jdd 11(3): 393-398
2012
ISSN/ISBN: 1545-9616 PMID: 22395592 Document Number: 10532
Interferon-α has been associated with a wide range of adverse events (AEs). A lupus-like reaction at the injection site of subcutaneous (SC) interferon-α is exceptionally rare. A 60-year-old woman with recurrent metastatic melanoma repeatedly developed cutaneous lupus-like reactions at the SC interferon-α-2b injection sites on her thighs. Known features of lupus-like reactions at SC interferon-α injection sites are reviewed, and cutaneous injection site reactions to SC interferon-α are summarized.
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