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Thin layer chromatographic identification of some sympathomimetic amines

Shah, J.J.; Shah, R.J.

Journal - Association of Official Analytical Chemists 59(6): 1416-1418

1976

ISSN/ISBN: 0004-5756
PMID: 11205
Document Number: 104730
Thin layer chromatographic behavior of some sympathomimetic amines in the presence of acids in neutral and organic solvent systems is reported. The sympathomimetic amines were dissolved in 0.1N HCl or ethanol and treated with bromocresol green or p-nitrobenzoyl chloride reagents on fiber sheets or precoated glass plates. Two-, 3-, and 4-, component solvent systems were tested. Benzene-ethyl acetate gave 2 spots for each amine standard; the more polar spots were satisfactorily separated. Amines in pharmaccuticals were not separated by any solvent system tested.

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