Unusual distribution of fluorescent marking during Schistosoma mansoni schistosomiasis

Niel, G.; Rosin, G.; Danis, M.; Gentilini, M.

Pathologie-Biologie 24(4): 277-282

1976


ISSN/ISBN: 0369-8114
PMID: 778761
Document Number: 104101
The sera of some patients suffering from intestinal bilharziasis determine, on frozen sections of adult S. mansoni, a labelling of the digestive tract disclosed by the fluorescent sera anti-IgG and IgM. This labelling appears early after the primary infestation and may remain isolated. It is found again later, among West Indian patients of all ages infested by S. mansoni. Its development is followed in the hamster and the mouse, experimentally infested. This labelling is also present in the animal infested with S. haematobium, but it appears exceptional among adults urinary bilharzians. No cross reaction of non-specific origin has been observed. The interest, for the screening, of its research with the help of conjugates anti-IgM, has been proved. Its meaning is discussed.

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