Elevated nitroblue tetrazolium dye reduction test response in acute viral respiratory disease
Sieber, O.F.; Wilska, M.L.; Riggin, R.
Pediatrics 58(1): 122-124
1976
ISSN/ISBN: 0031-4005 PMID: 180486 Document Number: 103595
Increased NBT dye reduction test responsiveness of neutrophil leukocytes was observed in 14 of 17 infants with acute viral respiratory syndromes. Syndromes studied included croup, bronchiolitis and pneumonia and were caused by parainfluenza virus types 1, 2 and 3, respiratory syncytial virus, influenza A virus, and adenovirus 1. NBT test elevation occurred early in every case of bronchiolitis and viral pneumonia and was associated with infections by all groups of viruses. NBT test results were normal or near-normal in a majority of cases of upper airway disease such as croup.