Thrombocyte lactate dehydrogenase isoenzymes in patients with ischemic stroke
Khmara, N.F.; Antonov, I.P.; Trukhan, A.S.
Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 76(7): 1009-1012
1976
ISSN/ISBN: 0044-4588 PMID: 961281 Document Number: 103512
It was established that in the acute period of the ischemic stroke in the maiority of cases a change of isoenzyme structure of LDG thrombocytes was due to a decrease of LDG3 activity. In a number of patients the dominant change in the spectrum was determined by LDG and LDG4 fractions. The changes were of a stable character up to 10 weeks. LDG4 increase was characteristic of the isoenzymes spectrum in the patients with a severe development of the disease and in the patients in the remote period of the stroke. The obtained data can serve as a criterion for evaluating the adaptive changes in acute brain ischemia.