Calcium-dependence of bradykinin-induced contraction in the isolated longitudinal muscle of the guinea pig ileum

Paegelow, I.; Reissmann, S.; Arold, H.

Acta Biologica et Medica Germanica 35(7): K51-K56

1976


ISSN/ISBN: 0001-5318
PMID: 1015158
Document Number: 101454
The calcium-dependence of the bradykinin-induced contraction was demonstrated on the isolated logitudinal smooth muscle of the guinea-pig ileum. Using the "La-method" for measuring 45Ca entry into smooth muscle cells we were able to show, that bradykinin significantly increases the intracellular Ca-concentration. This effect of bradykinin was dose-dependent.

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