Influence of H-2 on the ontogenesis of a spleen cell population which lacks C3 receptors and Thy-1 antigen

Ferreira, A.; Nussenzweig, V.

Journal of Immunology 117(3): 771-773

1976


ISSN/ISBN: 0022-1767
PMID: 1085310
Document Number: 101400
During ontogeny there are marked differences in the cellularity of the spleen of mice from different inbred strains. Data from segregation analysis demonstrated that one of the genes involved in the control of the size of the spleen at 15 days lies in the H-2 complex. In contrast to previous reports, it was found that the cell population under H-2 influence lacks complement receptors.

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