Kidney ultrastructure in experimental lithiasis and nephrocalcinosis
Blagodarov, V.N.
Biulleten' Eksperimental'noi Biologii i Meditsiny 81(4): 494-496
1976
ISSN/ISBN: 0365-9615 PMID: 1084176 Document Number: 101225
An experimental electron-microscopic study of the kidneys was carried out in experimental oxamide nephrolithiasis in rabbits and hypervitaminosis D in rats. The most pronounced changes were revealed in the proximal and the distal convoluted tubules. It is suggested that cytosomes and lysosome-like bodies possibly participated in stone formation and nephrocalcinosis. It is supposed that they played an important role in the morphogenesis of nephrolithiasis man.