The Discrepancy between Electrophoretic and Nephelometric Determinations of Serum γ-Globulin Level
Morita, K.; Okamoto, Y.
Clinical Laboratory 50(7-8): 415-418
2004
ISSN/ISBN: 1433-6510 PMID: 15330509 Document Number: 10085
We studied the significance of discrepancies in correlation between serum Γ-globulin levels electrophoretically estimated and immunoglobulin levels nephelometrically determined. Discrepancies appeared in cases with IgA myeloma, macroglobulinemia, and rare types of dysgammaglobulinemia frequently overlooked in serum electrophoresis, IgD myeloma and Γ-heavy chain disease. It is suggested that comparison of the Γ-globulin levels by the different methods is a simple and useful method of detecting these dysgammaglobulinemias.
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