Heterologous sera: a target for in vitro cell-mediated cytotoxicity
Forni, G.; Green, I.
Journal of Immunology 116(6): 1561-1565
1976
ISSN/ISBN: 0022-1767 PMID: 178800 Document Number: 100704
During the course of studies in inbred Strain 2 Guinea pigs on in vitro cell-mediated cytotoxicity to viral induced fibrosarcomas, it was observed that fetal calf serum in the medium in which the target cells were grown was responsible in some instances for much of the cytotoxicity observed. This fetal calf serum-specific cytotoxicity seemed mainly mediated by T cells and appeared to be independent on histocompatibility between target and killer cells.
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