Effect of anti-inflammatory drugs on lipase in vitro
Zwarenstein, H.; Sapeika, N.; Holmes, J.H.
Research Communications in Chemical Pathology and Pharmacology 13(3): 563-565
1976
ISSN/ISBN: 0034-5164 PMID: 935643 Document Number: 100596
Mefenamic acid, and to a lesser extent, flufenamic acid have a significant inhibitory effect on lipolysis as determined by the action of mouse pancreas lipase on the dilauric (didodecanoic) acid ester of fluorescein. Ibuprofen, fenoprofen calcium, phenylbutazone, oxyphenbutazone and alclofenac had comparatively little effect.
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