Detection of viral hepatitis type a
Hollinger, F.B.; Bradley, D.W.; Dreesman, G.R.; Melnick, J.L.
American Journal of Clinical Pathology 65(5 Suppl): 854-865
1976
ISSN/ISBN: 0002-9173 PMID: 218440 Document Number: 99918
Several technics are currently being used to detect hepatitis type A antigen or its antibody. These include immunoelectronmicroscopy, immune adherence, and complement fixation. This paper describes another promising technic, a microtiter solid-phase immunoradiometric assay, in which hepatitis A antigen and antibody are detected. Such a method can be utilized for biochemical and biophysical analysis of purified particles, for the seroepidemiology of type A hepatitis, and as a means for monitoring hepatitis A antigen in cell cultures.