The centrineurogenic etiology of the respiratory distress syndrome: protection by unilateral chronic pulmonary denervation in hemorrhagic shock

Moss, G.; Stein, A.A.

Journal of Trauma 16(5): 361-364

1976


ISSN/ISBN: 0022-5282
PMID: 775115
Document Number: 98314
Anemic beagles were subjected to 40 mm Hg hemorrhagic shock for 2 hours, which uniformly induced the pulmonary lesions of the "respiratory distress syndrome" (RDS) bilaterally in all six controls. For six subjects with complete denervation of the left lung 2 months previously, the shock regimen induced the lesions in the normally innervated right lungs; all reimplanted, denervated left lungs remained anatomically intact. This is presented as additional evidence for a centrineurogenic etiology for RDS.

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