Formation of immune distress syndrome in patients with combined course of chronic obstructive pulmonary disease and chronic pancreatitis
Zhelezniakova, N.
Georgian Medical News 214: 19-23
2013
ISSN/ISBN: 1512-0112 PMID: 23388529 Document Number: 669353
The aim of the article was to study the peculiarities of the development of the metabolic intoxication and the formation of autoimmune reactions in patients with combined course of chronic obstructive pulmonary disease (COPD) and chronic pancreatitis. The features of formation metabolic intoxication and autoimmune reactions in patients with combined course of COPD and chronic pancreatitis were revealed. It was found that the presence of concomitant chronic pancreatitis exacerbates the syndrome of endogenous intoxication and the imbalance of regulatory mechanisms of both cellular and humoral immunity significantly increases the risk of autoimmune complications. This fact allows us to consider the presence of concomitant chronic pancreatitis in patients with COPD as unfavorable prognostic factor.