Rhabdomyolysis associated with quinacrine therapy in a patient with chronic cutaneous lupus erythematosus

Creel, N.; Werth, V.

Journal of Drugs in Dermatology Jdd 4(2): 225-227

2005


ISSN/ISBN: 1545-9616
PMID: 15776783
Document Number: 9809
We describe a patient who developed rhabdomyolysis 6 weeks after starting combination therapy with hydroxychloroquine and quinacrine for the treatment of chronic cutaneous lupus erythematosus (CCLE). Myopathy due to 4-aminoquinolone antimalarials has been well documented. It is plausible that quinacrine may induce muscle injury in a manner similar to other antimalarials but, to our knowledge, rhabdomyolysis associated with antimalarial therapy has not been reported.

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Rhabdomyolysis associated with quinacrine therapy in a patient with chronic cutaneous lupus erythematosus