Recurrent injection site reactions from interferon beta 1-b
Samuel, L.; Lowenstein, E.J.
Journal of Drugs in Dermatology Jdd 5(4): 366-367
2006
ISSN/ISBN: 1545-9616 PMID: 16673806 Document Number: 9765
Recombinant human interferon beta-1b is an immune-modulatory drug used for a variety of conditions including multiple sclerosis (MS). Skin reactions to therapeutic use of injectable interferon beta-lb are relatively common, including injection site reactions and exacerbation of underlying skin disease. Injection site reactions are seen much more frequently in females. We discuss a case of prolonged susceptibility to injection site reaction with over a decade of use of interferon beta 1-b for MS. Given the prevalence of such reactions, the dermatologist should be aware of the phenomenon and that it frequently does not necessitate discontinuation of therapy.
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