LDH isoenzymes and gastrin in achlorhydri
Mohamedi, S.; Penner, E.; Brunner, H.; Sinzinger, H.; Pietschmann, H.
Wiener Klinische Wochenschrift 88(14): 458-460
1976
ISSN/ISBN: 0043-5325 PMID: 960704 Document Number: 97414
Several haematological findings (especially the values of serum LDH and its isoenzymes) were compared with changes in the gastrin level in pernicious anaemia. While vitamin B12 substitution therapy led to normalization of the anaemia and of the enzyme levels, gastric atrophy and, hence, the elevation in serum gastrin levels remained unchanged. Determination of serum gastrin, therefore, provides a valuable tool for the verification of the diagnosis of pernicious anaemia in treated cases.