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Investigation of the choleretic action of febuprol on healthy test subjects

Wolf, C.; Ritter, U.; Zschocke, R.; Weinert, W.

Münchener Medizinische Wochenschrift 118(40): 1285-1288

1976

ISSN/ISBN: 0341-3098
PMID: 824554
Document Number: 96870
The choleretic effect of 3-butoxy-1-phenoxypropanol-(2), Febuprol (INN), was examined in healthy volunteer subjects. In a dose range from 50 to 200 mg, the total bile is dose-dependent and excretion is significantly increased. The excretion of the bile constituents bile acids, bilirubin, cholesterol and phospholipids is increased proportionally with the bile secretion. The lithogenic index remains unaltered.

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