The problem of sterility in men and women after wide area sub-diaphragmatic irradiation
Dana, M.; Weisgerber, C.; Teillet, F.; Desprez-Curely, J.P.; Goguel, A.; Chotin, G.; Bernard, J.
Journal de Radiologie d'Electrologie et de Medecine Nucleaire 57(5): 405-408
1976
ISSN/ISBN: 0368-3966 PMID: 994090 Document Number: 96792
Sub-diaphragmatic irradiation in an upside down Y pattern for Hodgkin's disease results in sterility in the women. Protection consists of irradiating the lumbar chain only when possible or by displacement of the ovary before irradiation, and laterally for preference. Although subsequent pregnancy is then possible, the genetic risk remains. In the male, Y irradiation results in prolonged virtually complete azoospermia. Associated chemotherapy also causes definitive sterility in the male. Collection for a sperm bank before treatment is advised.