Adrenaline and cyclic AMP stimulation of ketopentose and sedoheptulose formation in rat liver homogenates
Kolotilova, A.I.; Glushankov, E.P.; Epifanova, I.E.
Ukrains'kyi Biokhimichnyi Zhurnal 48(4): 433-436
1976
ISSN/ISBN: 0041-610X PMID: 185767 Document Number: 96774
Formation of sedoheptulose-7-phosphate and ketopentose phosphate was studied in vitro as affected by epinephrine and cAMP. No effect of epinephrine on the activity of transketolase was found with ribose-5-phosphate as a substrate of the nonoxidative reactions of the pentose phosphate ccyle. Epinephrine and cAMP enhance the formation of ketopentoses and sedoheptulose with glycogen as a main carbohydrate source, which is most pronounced in the experiments with cold preincubation. The phosphorylase system mediate influence of epinephrine and cAMP on the nonoxidative reactions products may be assumed.