Antibody formation in swine vaccinated with a lapinized K-vaccine and serum against hog cholera
Dimitrov, K.; Gavrilov, N.
Veterinarno-Meditsinski Nauki 12(9): 40-45
1975
ISSN/ISBN: 0324-1068 PMID: 1239855 Document Number: 96137
Immunized were experimentally a total of 10 pigs with 2 cu. cm lapinized K vaccine and 10 cu. cm swine fever serum each. Reimmunization was performed a month later using only vaccine. After three and a half months the experimental pigs were included into the group of pigs producing serum against swine fever that were preliminary simultaneously immunized against hog cholera by the classical method. Swine fever antibodies in the serum of the experimental pigs showed a concentration that was equal to that in the serum of the regular donors as in both cases the serum titer ranged within the limits of 0.10 to 0.12 cu. cm per kilogram body weight. It is concluded that pigs intended for serum producers can be immunized with a lapinized K vaccine and serum against swine fever on the farms supplying the animals. After building up the basic immunity, which lasts about three and a half months the pigs could be bought over and included for serum production. Thus, the pathogenic hog cholera virus of the simultaneous immunization at the Institute (producer of serum) will be eliminated, economizing forage and labor and premises for several months, which are necessary for serum producing pigs.