The effects of polyamines on cardiac protein biosynthesis
Gibson, K.; Harris, P.
Recent Advances in Studies on Cardiac Structure and Metabolism 7: 71-76
1975
ISSN/ISBN: 0363-5872 PMID: 1226460 Document Number: 94635
Putrescine, spermine, and spermidine were able to stimulate cell-free protein biosynthesis at low Mg++ ion concentrations. The addition of polyamines to the perfusate of an isolated perfused rat heart preparation caused an increased rate of [14C]phenylalanine incorporation into myocardial protein. Spermine increased the uptake of alpha-aminoisobutyric acid into the myocardium.