Impaired phagocytic activity of human monocytes in respect to reduced antibacterial resistance in uremia
Urbanitz, D.; Sieberth, H.G.
Clinical Nephrology 4(1): 13-17
1975
ISSN/ISBN: 0301-0430 PMID: 1157344 Document Number: 93776
Resistance to bacterial infection, particularly septicemia and pneumonia, is decreased in patients with uremia. Tests of monocyte function in 21 patients with chronic uremia and in 21 normal healthy subjects showed an increase in attachment rate, spreading activity and Nirtoblue-tetrazolium reduction in the uremic subjects. In contrast, phagocytosis of IgG-coated red cells was impaired.